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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETDB1
All Species:
11.21
Human Site:
S493
Identified Species:
35.24
UniProt:
Q15047
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15047
NP_001138887.1
1291
143157
S493
Q
V
A
K
K
S
T
S
F
R
P
G
S
V
G
Chimpanzee
Pan troglodytes
XP_524864
1412
156345
T613
K
Q
V
A
K
K
S
T
S
F
R
P
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001106711
1328
147160
S530
Q
V
A
K
K
S
T
S
F
R
P
G
S
V
G
Dog
Lupus familis
XP_540304
1294
143238
K494
Q
S
R
K
Q
V
A
K
K
S
T
S
F
R
P
Cat
Felis silvestris
Mouse
Mus musculus
O88974
1307
144530
S492
Q
V
A
K
K
S
T
S
F
R
P
G
S
V
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INA9
1269
141759
Q488
P
G
S
A
G
S
G
Q
S
S
P
I
P
T
E
Zebra Danio
Brachydanio rerio
Q08BR4
1216
135792
S449
V
Q
Y
T
S
D
N
S
A
A
A
S
T
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392624
1059
120586
V292
V
V
A
I
F
K
D
V
S
S
N
F
Y
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
96.3
96.4
N.A.
91.3
N.A.
N.A.
N.A.
N.A.
68.4
54.6
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
100
91.2
96.5
97.5
N.A.
94.4
N.A.
N.A.
N.A.
N.A.
77.9
67.3
N.A.
N.A.
48.2
N.A.
N.A.
P-Site Identity:
100
6.6
100
13.3
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
26.6
100
20
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
25
0
0
13
0
13
13
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
0
13
0
0
0
38
13
0
13
13
0
0
% F
% Gly:
0
13
0
0
13
0
13
0
0
0
0
38
13
13
63
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
13
0
0
50
50
25
0
13
13
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
50
13
13
0
13
% P
% Gln:
50
25
0
0
13
0
0
13
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
0
0
0
38
13
0
0
13
0
% R
% Ser:
0
13
13
0
13
50
13
50
38
38
0
25
38
25
0
% S
% Thr:
0
0
0
13
0
0
38
13
0
0
13
0
13
13
0
% T
% Val:
25
50
13
0
0
13
0
13
0
0
0
0
0
38
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _